Tag

Tagged: epigenetics

Sponsored
joined 9 years, 10 months ago

Robert Brown

Chair Translational Oncology and Head of Division of Cancer, Imperial College London

Professor Robert Brown is Chair in Translational Oncology and Head of Division of Cancer within the Department of Surgery and Cancer at Imperial College, where he heads the Epigenetics Unit. His post is a joint appointment between Imperial College London and Institute of Cancer Research where he is the Epigenetics Team Leader in the Section of Molecular Pathology. Bob is Principal Investigator of a Cancer Research UK research programme, Drug Resistance and Epigenetic Mechanisms, and is a joint Principle Investigator of the Imperial Experimental Cancer Medicine Centre. He moved to London in 2007 after working for nearly 20 years at the CRUK Beatson Laboratories in Glasgow where he was Director of Laboratory Research in the Centre for Oncology and Applied Pharmacology. He obtained his BSc in Biological Sciences (Genetics) at Edinburgh University, his PhD at MRC Radiobiology Unit, Harwell, and his Post-doc at the German Cancer Research Centre, Heidelberg.

He has provided key insight into epigenetic mechanisms involved in tumorigenesis and resistance to chemotherapy, particularly in ovarian cancer. Recent areas of his research include; identifying novel epigenetic targets in ovarian and breast cancer, characterising histone marks and DNA methylation in breast and ovarian tumours as risk, prognostic and/or predictive biomarkers, and development of novel histone methyltransferase inhibitors.

He is Chair of the NCRI Biomarker and Imaging Clinical Studies Group whose remit is to facilitate and support biomarker and imaging studies in UK clinical trials. He is Deputy-Chair of CR-UK New Agents Committee and member of MRC Molecular and Cellular Medicine Board.


view this profile