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  • The rise of false medical information undermines healthcare delivery, fosters mistrust, and exacerbates health crises
  • Social media algorithms, human psychology, and influential personalities can drive the spread of inaccurate information
  • Transparent communication, strategic dissemination of information, and enhanced media literacy are essential for countering false narratives
  • AI can help detect and combat deceptive content, but robust policies and regulations are crucial for its effectiveness
 
Medical Misinformation

On May 20, 2024, the final report of a five-year public inquiry into the UK’s infected blood scandal, chaired by Sir Brian Langstaff, delivered a damning indictment of doctors, successive governments, civil servants and the NHS for misinforming patients about contaminated blood treatments, resulting in >30,000 infections with diseases like HIV and hepatitis C, and causing ~3,000 deaths, with additional fatalities anticipated.

A few hours after Langstaff issued his report, the UK Prime Minister, Rishi Sunak, addressed a packed House of Commons, expressing deep regret  for the failures, stating he was “truly sorry” and the attitude of denial was difficult to comprehend and an “eternal shame”. This scandal underscores a broader and growing concern about medical misinformation, where institutional failures and deliberate obfuscation contribute to public distrust and widespread harm. It highlights the need for transparency and accountability in healthcare systems worldwide.
 
In this Commentary

This Commentary traces the evolution of medical misinformation from myths about Edward Jenner’s late 19th century smallpox vaccine to recent falsehoods, highlighting the roles of digital platforms and socio-political factors. It emphasises the need for healthcare professionals to be vigilant, promote media literacy, advocate public education, and call for strong policies to counteract medical disinformation. Additionally, it examines the dual role of AI in both spreading and combating false health information. By considering an historical context, current challenges, and future strategies, the Commentary aims to enhance understanding and provide solutions to mitigate the impact of medical misinformation on public health.
 
Dead Wrong

Medical misinformation manifests in two primary forms: misrepresenting effective therapies and promoting dangerous treatments. False claims, such as the debunked link between the MMR vaccine and autism, undermine public trust in vaccines, causing decreased vaccination rates and preventable disease outbreaks. Advocacy for harmful treatments, like the opioid epidemic in the US and the tobacco industry's promotion of smoking despite evidence of severe health risks, directly endangers patients and diverts resources from legitimate care. The rise of medical misinformation, fuelled by social media algorithms, human psychology, and influential personalities, exacerbates these threats by fostering harmful behaviours, distrust in medical professionals, and delays in appropriate care. Combating this requires transparent communication, strategic information dissemination, enhanced media literacy, and robust policies and regulations, with AI playing a role in detecting and countering false information to protect public health.
 
In their 2023 publication, "Dead Wrong: Diagnosing and Treating Healthcare’s Misinformation Illness," Geeta Nayyar et al trace the evolution of the phenomenon. One prominent consequence of medical misinformation is vaccine hesitancy, which has persisted from the era of the smallpox vaccine in the late 19th century to the digital age. The book delves into the socio-political dimensions of misinformation, illustrating how political leaders can contribute to vaccine hesitancy and societal divisions. Despite a consensus among researchers, health professionals, and policymakers on the imperative to combat health fabrications, the full scope of this issue remains elusive. Nayyar offers practical strategies for healthcare professionals to confront and reduce the phenomenon.

A 2023 study published in the Journal of Medical Internet Research found that the most prevalent medical falsehoods involve information about smoking, drugs, vaccines, and diseases, with Twitter (now known as ‘X’) identified as a primary platform for their dissemination. Social media amplifies the spread of health misinformation, eroding public trust and impeding medical advancements.
Digital Amplification

Addressing medical falsehoods is important in an era where information spreads rapidly through digital channels. The rise of social media and increased internet accessibility allow misinformation to reach vast audiences within seconds. This challenge is compounded by advancements in AI, which, while contributing to healthcare improvements, also create new avenues for generating and disseminating false information.
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AI technologies, particularly deep learning and natural language processing, can produce convincing fake content, including medical advice and research findings, exploiting public anxieties and knowledge gaps. To combat this, it is essential to enhance digital literacy, improve the accuracy of AI systems, and foster collaboration among technology companies, healthcare professionals, and policymakers. By understanding and addressing the sources and impacts of medical falsehoods, the protection of public health can be enhanced.
 
Historical Context

Medical misinformation has a long history, dating back to the late 18th century when Edward Jenner, an English physician and scientist known as the father of immunology, pioneered the concept of vaccines and created the world's first smallpox vaccine. Despite its success, Jenner faced significant opposition, fuelled by fear and misunderstanding. Critics spread false claims that vaccination could cause various ailments or even transform individuals into cow-like creatures due to the cowpox origin of the vaccine. This early example highlights the challenges of medical misinformation: fear, misunderstanding, and resistance to new scientific advancements.
 
Throughout the 19th and 20th centuries, the printing press enabled the widespread dissemination of both accurate and inaccurate information. Pamphlets and newspapers often spread falsehoods about anaesthesia and germ theory. The rise of mass media, including radio and television, further amplified inaccurate health information. A notable example is the mid-20th century polio vaccine scare, known as the Cutter Incident, which occurred in April 1955. This involved a batch of polio vaccines produced by Cutter Laboratories that contained live poliovirus, leading to cases of polio among vaccinated children. The Cutter Incident eroded public confidence in the polio vaccine and prompted changes in vaccine production and safety protocols. Additionally, misinformation surrounding the HIV/AIDS epidemic in the late 20th century created fear, stigma, and ignorance as the HIV epidemic raged throughout the world in the 1980s, killing thousands of people.
 
The advent of the internet and social media in the late 20th and early 21st centuries increased the speed and reach of misinformation. Anti-vaccine activism gained traction with the publication of Andrew Wakefield’s now-debunked study in 1998, which falsely linked the MMR (measles, mumps and rubella) vaccine to autism. This led to declines in vaccination rates and subsequent outbreaks of preventable diseases. The COVID-19 pandemic, declared by the World Health Organisation (WHO) in March 2020, further highlighted the impact of medical misinformation, as falsehoods complicated public health efforts and contributed to vaccine hesitancy.
 
Sources and Mechanisms of Medical Misinformation

As we have suggested, medical misinformation spreads through social media platforms, traditional news outlets, and the misinterpretation of scientific studies. Social media platforms like Facebook, X (formerly Twitter), TikTok, and Instagram serve as potent conduits due to their extensive reach and rapid information dissemination capabilities. Often, these platforms lack stringent content inspection mechanisms, enabling unverified information to proliferate through algorithms designed to maximise engagement, which inadvertently prioritises misleading content. Traditional media also contributes to the problem by sensationalising news to attract attention, without adequate fact-checking.
 
Misinformation often goes viral more easily than factual information. A 2018 study in the journal Science found that false information is 70% more likely to be retweeted than the truth. Influencers with large followings further exacerbate the issue by sharing inaccurate information, which quickly gains credibility through their endorsements. Addressing medical misinformation requires a multifaceted approach, including enhanced verification processes, increased public education, and greater accountability for those spreading false information. Additionally, adjusting algorithms, improving media literacy, and promoting credible medical sources are essential steps in combating this pervasive issue.
  
Consequences

Vaccine hesitancy, driven by falsehoods spread online and through social networks, leads people to doubt vaccine safety and efficacy. This hinders vaccination efforts and increases outbreaks of preventable diseases. Inaccurate medical information erodes trust in healthcare professionals and institutions, undermining expert guidance and fuelling public uncertainty and fear. This hampers healthcare delivery and weakens community resilience in crises. Individuals misled by medical falsehoods may make harmful health decisions, such as avoiding recommended treatments or trying dangerous alternative therapies. These effects threaten both personal health and community wellbeing.
 
Case Studies

We have mentioned these examples before, but due to their significance, we are now giving them more prominence.

Smallpox Vaccine Opposition
When Edward Jenner introduced the smallpox vaccine in 1796, scepticism and resistance emerged. Misconceptions about its safety and efficacy, coupled with religious and philosophical beliefs, led some to argue that vaccination interfered with divine will. This resistance delayed smallpox eradication, causing continued outbreaks and fatalities. Persistent public health campaigns and legislative actions eventually overcame this opposition.
 

MMR Vaccine Scandal
In 1998, Andrew Wakefield published a fraudulent research paper falsely linking the MMR vaccine to autism. Despite lacking credible scientific evidence, the publication caused a significant decline in vaccination rates due to media coverage and public fear, leading to outbreaks of measles and other preventable diseases. Subsequent investigations revealed Wakefield's ethical violations and data manipulation, resulting in the retraction of the paper and the revocation of his medical license.

UK Contaminated Blood Scandal
Bleeding disorders are conditions that impair the blood's ability to clot properly. In the UK, ~24,000 people live with such disorders, which are typically inherited, although ~33% of cases result from random gene mutations. The most well-known bleeding disorder is haemophilia A, predominantly affecting males. Those living with the disorders often require transfusions of blood platelets or clotting factors.

Between 1950 and 1970, UK authorities sourced blood donations from prisons. However, the introduction of screening for hepatitis B in the early 1970s revealed a significantly higher incidence of the disorder among inmates. Despite aiming for self-sufficiency in NHS blood stock by July 1977, the UK government failed to achieve this goal and relied on imported blood and blood from prison donors for decades. While countries like Germany and Italy began testing donated blood in the mid-1960s and early 1970s, and the American Red Cross stopped collecting blood from US prisons in 1971 due to high hepatitis rates, the UK continued to import Factor VIII - a blood clotting product - from high-risk US donors, including prison inmates and intravenous drug users, during the 1970s and 1980s. The contaminated blood products led to ~30,000 people in the UK being infected, causing ~3,000 premature deaths. Many survivors contracted HIV and hepatitis C and faced additional challenges such as stigma, job loss, and financial hardship. In 2018, Sir Brian Langstaff was appointed to chair a public inquiry into the UK's contaminated blood scandal. His final report, released on May 20, 2024, highlighted that many infections were preventable and concluded that the tragedy was exacerbated by decades-long cover-ups by doctors, the NHS, governments, and civil servants, driven by "financial and reputational considerations." Langstaff called for immediate compensation, public memorials, and systemic reforms.


The US opioid epidemic
The on-going opioid epidemic in the US further illustrates the impact of medical misinformation. Every day, ~300 Americans die from drug overdoses. According to the Centers for Disease Control and Prevention, there were >100,000 reported overdose deaths in 2021, with opioids involved in ~75% of these cases. Pharmaceutical companies played a significant role in this crisis by misleading healthcare providers and patients, downplaying the addictive risks of opioids, and falsely claiming they were safe for chronic pain management. This misinformation led to widespread over-prescription, resulting in addiction and overdose deaths. Consequently, the opioid epidemic has fuelled a persistent public health crisis that continues to challenge the nation.
 
Combating Medical Misinformation

Effectively combating medical misinformation is challenging, especially when governments and healthcare systems are involved. Addressing this phenomenon requires a multifaceted approach, including proactive public health communication, the involvement of trusted community leaders, and robust social media monitoring. Healthcare professionals and institutions must provide accurate, evidence-based information and act as trusted voices in their communities. Their proactive engagement in patient education and public outreach helps dispel myths and correct falsehoods.
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Equipping individuals with critical thinking skills to evaluate information sources is essential. Effective strategies to combat misinformation involve utilising a variety of platforms, from traditional media to social networks, ensuring messages reach a broad audience. Clear, consistent, and transparent communication is crucial for building trust and encouraging the public to follow health guidelines.
Policy and regulatory approaches also play an important role. Governments and healthcare organisations must implement regulations to curb the spread of false information, such as holding social media platforms accountable for monitoring and addressing misinformation. Policies should support the training of healthcare professionals in communication skills and media engagement, ensuring they are prepared to counteract misinformation effectively. Integrating these approaches can create a more informed public, enhance trust in healthcare systems, and ultimately improve health outcomes.
 
The Future

The future of medical misinformation will be shaped by emerging trends and technologies, presenting both challenges and opportunities. AI and machine learning (ML) can play roles in detecting and countering falsehoods. Advanced algorithms can analyse vast amounts of data to identify misinformation trends, flagging content that requires further scrutiny. AI-driven chatbots and virtual assistants can provide people with reliable health information, directly counteracting misinformation at its source.
 
Despite these advancements, the use of AI and ML also poses significant risks. These technologies can be exploited to create deepfakes, and if not properly managed, they can inadvertently amplify misinformation, as evidenced by algorithmic biases on social media platforms. To mitigate these risks, ensuring ethical AI deployment and incorporating robust human oversight is crucial. Fostering collaboration between tech companies, healthcare professionals, and policymakers can also establish robust frameworks for managing misinformation. By embracing these technologies while remaining vigilant about their limitations, we can help shape a future where accurate medical information prevails.
 
Takeaways

Geeta Nayyar deserves commendation for her book, which has raised awareness about medical misinformation. Historical and contemporary case studies highlight the evolving threat misinformation poses to public health. Accurate, transparent communication and robust public health strategies are needed. Despite the complexities of combating misinformation, especially when health professionals and governments are involved, healthcare institutions must proactively disseminate reliable information and be accountable for their actions. Media literacy and public education are essential for empowering individuals to navigate the complex information ecosystem. There is a need to leverage advanced technologies, such as AI and ML, which offer promising avenues for detecting and countering misinformation, provided they are implemented with ethical oversight. A multifaceted approach, including policy and regulatory measures, is crucial for safeguarding public health, enhancing trust in healthcare systems, and improving health outcomes.
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Who Should Consider Cosmetic Dentistry?
Do you cover your mouth when talking to others or feel embarrassed to smile or laugh because your teeth don’t look their best?

Cosmetic dentistry can help, from treating minor imperfections to larger and more complex smile makeovers.

Treatment is worth considering if you have the following problems:

  • Chipped or cracked teeth

From safe, effective teeth whitening to complete smile makeovers, we can help you achieve your dream smile.

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385 Prospect Ave, Suite 304,
Hackensack, NJ 07601
(201) 425–9580
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Why Do You Need a Family Dentist?
Each person has unique oral health care needs that change throughout life. As a family-oriented dental clinic, we can support people of all ages and look after everyone's oral health care needs in one comfortable location.

New Jersey Dentist is a multispecialty dental office offering a wide choice of different dental therapies and treatments.

Everyone visiting our practice receives a custom dental care plan. The plan is based on your dental exam, a review of your medical history and age, and any oral health concerns or desires. Each treatment provided is tailored to accommodate your unique oral health needs.

A family dentist can provide continuity of care so your children grow up trusting dentists and their dental team. A long-term relationship helps our dentist understand your family's oral care needs and provide more personalized care

What Is Family Dentistry?
A family dental office provides a variety of treatments designed to accommodate most oral health care needs. As a multispecialty dental office, we have state-of-the-art equipment and technologies that help us diagnose and treat conditions more efficiently and comfortably.

These technologies include:

  1. Digital x-ray equipment, including panoramic x-rays.
  2. Cone beam CT scan that provides digital 3-D images of teeth and jaws.
  3. 3D scanners for digital dental impressions are more comfortable and accurate than traditional tray impressions
  4. Intraoral cameras to take photos inside your mouth. These images can be magnified and shown on screen, allowing you to see what we see, and so we can explain treatments more easily.

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My New Jersey Dentist
385 Prospect Ave, Suite 304,
Hackensack, NJ 07601
(201) 425–9580
Web Address: https://mynjdentist.com/ 

Working Hours:
Monday-Friday: 10:00 am — 6:00 pm
Saturday: 9:00 am — 3:00 pm
Sunday: by appointment only

Payment: cash, check, credit cards.

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Dental implants are also called teeth implants and artificially replace missing tooth roots. They consist of metal screws that are inserted permanently into the jawbone during an oral surgery procedure. They can support artificial teeth, including dental crowns, bridges, and implants.

Who Would Need Dental Implants?
If you face losing one or more teeth, you will almost certainly benefit from dental implants. Tooth loss can occur due to the following reasons:

  • Tooth decay
  • Bruxism
  • Gum disease
  • Tooth root fractures
  • Facial trauma
  • Congenitally missing teeth
  • What Are Dental Implants?

A dental implant usually has three components. The first is the threaded screw that is placed into the jawbone. The second is a connector or abutment that is attached to the screw. The third and final component is the implant restoration.

Implant Restorations
When a single implant is placed, this can be an implant crown. Multiple implants can restore teeth using an implant bridge. Implant crowns and bridges are non-removable. They are screwed or cemented onto the abutments

Dental implants can support a removable implant denture. Instead of being screwed or cemented in place, the implant denture clips onto the abutments or a metal bar attached to the abutments.

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Nearby Locations & Municipalities:
Maywood | Teaneck | Lodi | Little Ferry | Ridgefield Park | Hasbrouck Heights | River Edge | Saddle Brook | Palisades Park | New Milford | Garfield | Englewood | Bergenfield | Ridgefield | Elmwood Park

Nearby Zip Codes
07601 | 07602 | 07603 | 07604 | 07666 | 07644 | 07643 | 07660 | 07657 | 07661 | 07663 | 07663 | 07650 | 07646 | 07631 | 07632 | 07621 | 07657


My New Jersey Dentist
385 Prospect Ave, Suite 304,
Hackensack, NJ 07601
(201) 425-9580

Web Address: https://mynjdentist.com/ 

Working Hours:
Monday-Friday: 10:00am - 6:00pm
Saturday: 9:00am - 3:00pm
Sunday: by appointment only

Payment: cash, check, credit cards.

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  • Healthcare is shifting from uniform treatments to personalised care, driven by genetics, lifestyle, and technology
  • Patients benefit from targeted therapies that deliver early disease detection, enhanced therapies and proactive prevention
  • Traditional MedTechs, accustomed to one-size-fits-all devices, face challenges but also can find opportunities from individualised care for growth and innovation
  • To capitalise on these opportunities, conventional corporations must recalibrate their strategies and collaborate with start-ups and healthcare institutions
 
The Impact of Personalised Healthcare on Traditional MedTechs

Personalised medicine, also known as precision medicine, marks a departure from traditional medical practices by acknowledging the interplay of genetics, lifestyle, and environment in shaping an individual's health. Rather than adhering to one-size-fits-all treatments, individualised care prioritises early detection and proactive prevention, tailoring interventions based on each patient's unique genetic makeup. Digitalisation, together with advances in medical technology, enables the combination and analysis of genomic information with other diagnostic data to identify patterns that help to determine an individual’s risk of developing a disease, detect illness earlier, and determine the most effective interventions. For example, in cancer treatment, personalised therapies target specific proteins driving cancer growth, offering more effective alternatives to conventional methods like customary chemotherapy. Findings of a 2012 study published in Trends in Molecular Medicine found that the response rate to a targeted therapy for acute myeloid leukaemia to be at 90% compared with 35% for standard chemotherapy. Another notable development in customised care is the DNA medication pass, which enables clinicians to identify the most suitable drugs for individual patients, reducing adverse reactions and hospital admissions due to drug-related complications. Such personalised approaches empower patients with treatments aligned to their genetic predispositions and foster greater autonomy and engagement in healthcare decisions.

In today's data-driven environment, the emphasis on precision care is growing, and creating a shift in healthcare delivery. A recent research paper published in the Journal of Translational Medicine suggests that personalised medicine will lead to the next generation of healthcare by 2030. While many traditional medical technology companies are content with supplying standardised medical devices to hospitals, an increasing number wish to pivot and capitalise on the rapidly growing targeted healthcare segment. However, they face the challenge of adapting their established frameworks, which are not designed to create bespoke solutions and services. This emphasises the significance of adaptability across diverse healthcare settings. Forward-thinking corporations, however, recognise the need to evolve. By investing in novel R&D initiatives and fostering collaboration throughout the healthcare spectrum, they position themselves favourably. Conversely, companies resistant to change risk stagnation and eventual obsolescence in an era where personalised care is rapidly gaining traction.

 
In this Commentary

This Commentary delves into the impact of personalised healthcare on traditional MedTech companies, highlighting the imperative for alignment with customised care to remain competitive. It explores how targeted medicine, driven by advancements in genetics, digitalisation, and medical technology, is reshaping healthcare delivery by prioritising individualised treatments tailored to patients' unique genetic makeup. The Commentary emphasises the need to adapt conventional strategies amidst industry trends, addressing challenges such as regulatory complexities and technology adoption barriers. Through initiatives like partnerships, novel R&D, diversification, and strategic M&A, traditional MedTechs can position themselves to lead in the era of precision care. The Commentary offers examples of start-ups and established firms addressing this segment, insights into the opportunities and challenges traditional companies face in adapting to the growing emphasis on personalised healthcare, and emphasises the importance of innovation, collaboration, and proactive responses to industry shifts.
 
Brief History

The roots of personalised healthcare can be traced back to ancient civilisations where healers recognised individual differences in response to treatments. However, formalised concepts began to emerge in the late 19th and early 20th centuries with the advent of modern medicine. The discovery of the structure of DNA by James Watson and Francis Crick in 1953 laid the foundation for understanding the role of genetics in health and disease. Advances in DNA sequencing technologies in the late 20th century, particularly the completion of the Human Genome Project in 2003, enabled scientists to decipher the entire human genetic code, ushering in the genomic era.
 
In the late 20th century, researchers began to explore how genetic variations influence an individual's response to drugs. Pharmacogenomics emerged as a field focused on tailoring drug treatments to a person's genetic makeup, aiming to maximise efficacy and minimise adverse effects. Rapid advancements in technology, such as next-generation sequencing and high-throughput screening, have made it more feasible and cost-effective to analyse large amounts of genetic data. This has accelerated research in tailored therapies and expanded their application beyond pharmacogenomics to include risk assessment, disease diagnosis, and treatment selection.
As we suggested, one of the earliest and most successful applications of customised healthcare has been in oncology. Precision oncology uses genomic profiling to identify genetic mutations driving cancer growth and matches patients with targeted therapies designed to address their specific mutations. The success stories in treating certain cancers, such as leukaemia and melanoma have fuelled further interest and investment in personalised approaches.
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The rise of big data analytics and artificial intelligence (AI) has been instrumental in advancing targeted care. By integrating genetic, clinical, lifestyle, and environmental data, AI algorithms can identify patterns, predict disease risks, and recommend precise interventions targeted to an individual’s unique profile. Governments have recognised the potential of these approaches to improve patient outcomes and reduce healthcare costs. Endeavours such as the Precision Medicine Initiative in the US, the NHS Long Term Plan in the UK, and similar efforts in other countries aim to accelerate the adoption of customised medicine. As technology continues to evolve and our understanding of genetics and biology deepens, personalised healthcare is poised to become increasingly integral to mainstream medical practice, ultimately leading to better health outcomes.
 
Challenges and Barriers to Personalised Care

Customised medicine, while promising, faces challenges. One hurdle lies in the complexity and sheer volume of data required to tailor treatments to individual patients. Integrating diverse datasets from genomics, medical history, lifestyle factors, and environmental influences demands sophisticated analytics and robust privacy safeguards. Additionally, interoperability issues between different healthcare systems impede data exchange and collaboration among healthcare providers. Economic constraints further obstruct widespread adoption, as customised therapies often come with hefty price tags, limiting access for many patients. Regulatory frameworks must also evolve to accommodate the dynamic nature of tailored medicine, ensuring rigorous oversight without stifling innovation. Moreover, educating healthcare professionals and patients about the benefits and limitations of personalised approaches is essential for fostering trust and acceptance. Overcoming these challenges demands interdisciplinary collaboration, technological advancements, and a commitment to equitable access to focussed healthcare.
 
The Changing Landscape of Traditional MedTechs

Despite these challenges, the growing emphasis on personalised care represents a shift in traditional MedTech markets. Although the precise timeline for tailored therapies to substantially influence conventional corporations remains uncertain, the trend signals a clear direction for the industry. The International Consortium for Personalised Medicine (ICPerMed) envisions a healthcare landscape firmly rooted in customised medicine principles by 2030. This vision entails an ecosystem where individual characteristics inform diagnostics, treatments, and preventive measures, resulting in heightened effectiveness and economic value, all while ensuring equitable access for all individuals.
 
Historically, MedTech markets have exhibited a degree of reluctance in adopting new technologies, offering some comfort to conventional leaders in the field. However, the insights provided by the ICPerMed research should serve as a catalyst for traditional enterprises to re-evaluate their strategies and product offerings if they intend to capitalise on the growing trend of customised care. Notably, investments in innovative technologies that facilitate precision diagnostics, targeted therapies, and patient-centric interventions have already proven effective and are on the rise.
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Furthermore, the integration of data analytics and remote monitoring capabilities is reshaping the dynamics among medical devices, patients, and healthcare providers. This integration fosters enhanced connectivity and delivers real-time insights, thereby helping to transform the healthcare ecosystem. As tailored care gains momentum, traditional corporations must embrace agility, collaboration, and an understanding of patient preferences to thrive. This necessitates a proactive re-evaluation of their strategies.
Healthcare Firms Leading the Shift Towards Personalised Care

Many early-stage MedTech companies and established healthcare firms are leveraging evolving technologies and data to meet the growing demand for personalised healthcare. Omada Health, for instance, offers a platform combining connected devices and data analytics to help manage chronic conditions through tailored lifestyle interventions. iRhythm Technologies' Zio patch, a wearable cardiac monitor, uses advanced algorithms to detect heart conditions more accurately. Butterfly Network's Butterfly iQ is the first smartphone-connected whole-body ultrasound system, enhancing imaging quality and diagnostic capabilities through AI. Mature enterprises like AliveCor and Fitbit, now part of Google, have also pivoted to tailored healthcare. AliveCor’s  KardiaMobile provides at-home ECGs and shares data for customised treatment plans, while Fitbit offers devices with advanced health monitoring features and personalised wellness programmes. Dexcom's G6 CGM System provides real-time glucose tracking integrated with health data platforms. Roche has shifted towards customised healthcare with digital health solutions like the Roche Diabetes Care platform and the NAVIFY Tumor Board for personalised cancer treatments. 23andMe, initially known for genetic testing, now partners with pharmaceutical companies for drug discovery and develops tailored treatment plans based on genetic data.
 
Transforming MedTech in the Era of Personalised Care

The healthcare industry is undergoing a transformation marked by a shift towards patient-centric care and the adoption of value-based healthcare models. This shift is driving increased collaboration among traditional MedTech firms, healthcare providers, and emerging players, all united in their goal to innovate and tackle the complex challenges facing healthcare today. Regulatory changes and technological advancements also are playing roles in reshaping the competitive landscape, guiding the industry towards more patient-centred, value-driven, and collaborative approaches. In response to these evolving dynamics, MedTech companies are transforming their product development strategies by embracing agile and interdisciplinary approaches. Leveraging digital technologies, they are adapting to changing demands through virtual testing, data-driven design optimisation, and rapid prototyping.
 
The move towards personalised care is not only transforming product development strategies but also reshaping business models within the MedTech industry. There is a growing emphasis on outcome-based pricing and service-oriented solutions, reflecting the industry's focus on delivering measurable results and comprehensive care experiences. Digital health platforms and software-as-a-service (SaaS) offerings are emerging as key drivers of revenue, highlighting the importance of innovation and customer engagement in staying competitive and relevant.
 
Amid these transformations, regulatory and compliance considerations are crucial. Regulatory frameworks are becoming more stringent, emphasising product safety, efficacy, and data privacy. Compliance with varying standards across geographies is essential for market access, requiring companies to navigate these landscapes skilfully to sustain growth. Regulatory bodies are also evolving to tackle emerging challenges like cybersecurity and interoperability, highlighting the need for effective regulatory management in today's MedTech ecosystem. Addressing these challenges demands collaboration among stakeholders to build trust, promote standards, and ease the adoption of innovative technologies. Only through concerted efforts can the industry overcome these obstacles and fully realise the potential of customised care in transforming healthcare delivery.
 
Adaptation Strategies for Traditional MedTech Companies

To strengthen their alignment with personalised healthcare, traditional MedTechs can adopt several strategies. One effective approach, which, in a previous Commentary, we referred to as the Third Way, involves forming partnerships and collaborations with start-ups, research institutions, or other industry players. Through these partnerships, corporations can gain access to novel technologies, broaden their market reach, and expedite the pace of innovation. Additionally, diversification emerges as another adaptation strategy, enabling companies to venture into adjacent markets or therapeutic areas. This not only helps in mitigating risks but also enables them to capitalise on emerging opportunities within the healthcare landscape. Furthermore, many traditional corporations opt for M&A to bolster their market position, acquire specialised capabilities, or tap into new customer segments. Collectively, these strategies empower traditional corporations to navigate industry transitions towards customised care, foster sustained growth, and uphold their competitive edge.
 
Takeaways
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This Commentary highlights the need for companies to re-evaluate their strategies in response to the industry's shift toward personalised care, a force shaping the future of healthcare delivery. It suggests traditional enterprises should proactively address challenges such as regulatory compliance, data security, and technological adoption barriers. Yet, within these challenges lie significant opportunities for growth and innovation. By pursuing strategic partnerships, investing in R&D, diversifying, and engaging in M&A, corporations can lead in the era of customised care, influencing healthcare's trajectory. Despite obstacles, the outlook for traditional enterprises is promising, driven by technological advancements and global healthcare demands. Success, however, depends on their agility, resilience, and proactive adaptation to the evolving landscape. By leveraging innovation and fostering collaboration, traditional MedTechs can navigate complexity and continue to drive positive transformation within the industry.
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Over the years, our dental center gained a local reputation for excellent and gentle dental care, using the latest state-of-the-art equipment and cutting-edge technology, upholding the strictest sterilization techniques. Many people may feel anxious about visiting the top-rated dentist, so we aim to make your visit with us as pain and anxiety-free as possible. Our mission is to educate our patients about all of their oral health care options and help guide them to choose a treatment plan that is most suitable and appropriate for their needs.

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NYC Eye Physicians are proud to be on USA Newsweek’s list of 350 best ophthalmologists and optometrists. Using the latest advancements and techniques in optometric practices, our doctors offer a full range of Optometry & Ophthalmology services, from eye exams and treatment for dry eyes, burning eyes, and eye stye to an accurate assessment of refractive errors, like nearsightedness/farsightedness/astigmatism, and eyeglasses or contact lenses. At Manhattan Eye Physicians, you’ll find the individualized, compassionate and patient-centric Optometry & Ophthalmology care you need in the safe, reassuring hands of eye experts.

To provide more comprehensive eye care, our optometrists use the newest diagnostic equipment available in the USA, such as Optical Coherence Tomography (OCT), Digital Slit Lamps, Automated Phoropters, Zeiss Visual Field Analyzers, VT1 Vision Screeners and Retina Cameras. These technologies offer earlier detection of various eye-related conditions and improved patient outcomes.

Eye Physicians
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Henry Wendt, 1933 - 2024
Obituary

Henry Wendt, born on July 19, 1933, in Neptune City, NJ, passed away on April 11, 2024, leaving behind a legacy that will endure for generations. Raised in Sands Point and Tuxedo Park NY, Henry embarked on a journey after graduating from Princeton University in 1955, starting his career as a salesperson for Smith, Kline & French, an American pharmaceutical company. His dedication and strategic acumen propelled him through various roles within the corporation, spanning locations such as Hawaii, Montreal, Tokyo, and Philadelphia, ultimately culminating in his appointment as President and CEO in 1976.
 
As CEO, Henry implemented a transformative 3-point strategy, reshaping the company's trajectory through strategic divestments and a focus on core products. This foresight laid the groundwork for the historic merger in 1989 with the UK-based Beecham Company, resulting in the formation of SmithKline Beecham (SKB). This was the largest cross-border merger of its time, and heralded the birth of a truly transnational corporation that would redefine global competition in the pharmaceutical industry. Under Henry's leadership, SKB emerged as the world’s second largest pharmaceutical company, both in prescription and over-the-counter drugs, solidifying its position as a global powerhouse.
 
Henry was more than just a businessperson; he was a visionary who recognised the significance of the evolving nature of transnational corporations. In his book, Global Embrace, published in 1993, he described a transition from the era of multinationals to the rise of transnational enterprises, painting a picture of a world where corporate operations transcended national borders in the pursuit of progress and prosperity. Henry's conceptualisation of transnational entities diverged from traditional multinationals primarily in their ownership structure. Unlike their predecessors, transnational corporations boasted a shareholder base that spanned the globe, marking a departure from the conventional reliance on temporary global marketing strategies like foreign branches, offshore acquisitions, joint ventures, or licensing agreements. This distinction emphasised a shift towards a more interconnected and globally oriented business paradigm. Henry's work not only explored market dynamics and competitive strategies but also explored the broader societal implications of this emerging corporate model, advocating for policies that fostered international cooperation and celebrated cultural diversity.

Henry Wendt's influence reached far beyond the boardroom, embodying integrity, moral fortitude, and an unwavering commitment to his country. His life epitomised timeless values of fairness, honesty, and optimism, evident in his many achievements and philanthropic endeavours. His diverse interests mirrored his commitment to improving society, seen through initiatives such as establishing academic chairs, sponsoring educational programmes, and funding research laboratories nationwide. A polymath, Henry found fulfilment in exploration, whether navigating the seas or delving into the realms of knowledge. Through ventures like the Quivira Estate Vineyards and Winery and his contributions to academia and research, his enduring impact continues to inspire future generations. In his passing, Henry Wendt leaves behind a rich legacy of leadership, generosity, and foresight that will echo through the years, serving as a powerful testament to the impact an individual can have on shaping a better world.

  
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  • MedTechs traditionally prioritise M&A over in-house R&D yielding size without always improving quality
  • Amidst healthcare's rapid evolution, companies must explore new avenues for growth and staying competitive
  • Embracing a Third Way, MedTechs can invest in start-ups to access disruptive technologies, mitigate risks, foster growth, and competitive advantage
 
A Third Way Growth Strategy for MedTechs
 
MedTech industry leaders must welcome fresh ideas to maintain their competitive edge and ensure ongoing growth. However, the conventional avenues of development, such as merger and acquisitions (M&A) and in-house research and development (R&D), often encounter obstacles that diminish their effectiveness. As the industry advances, companies face the dual challenge of adopting new technologies while breaking down entrenched organisational barriers. In an era marked by transformative breakthroughs and turbulent market forces, adaptability and innovation are indispensable drivers of success.
 
The line separating established enterprises from agile newcomers has blurred, paving the way for potential collaboration and strategic investment. To excel in this environment, traditional MedTechs should consider recalibrating their conventional growth strategies. Rather than solely relying on M&A or low-risk tweaks to in-house R&D, they should explore a Third Way: investing in and collaborating with a range of innovative start-ups. Giant MedTech have been doing this for decades and reaping the benefits of nascent enterprises, fuelled by high-energy talent, leveraging novel technologies, and offering a fresh approach to growth and value creation.
 
Collaborating with early-stage entities empowers traditional firms to foster a culture of innovation and adaptability, thereby improving patient outcomes and strengthening healthcare systems to thrive in an era of unprecedented change. Effectively managing inventiveness becomes imperative for traditional MedTech companies to successfully navigate the evolving healthcare ecosystem.

 
In this Commentary

This Commentary emphasises the importance for MedTechs to define a clear strategic path in response to the challenges posed by rapid technological advancements, geopolitical shifts, and advancing market dynamics. We propose a Third Way that moves beyond conventional strategies of M&A and internal R&D. We advocate for investment in a varied portfolio of innovative early-stage enterprises focused on developing disruptive healthcare solutions and services. This approach aims to avoid the drawbacks associated with conventional growth strategies and set up MedTechs for long-term growth and improved competitiveness.
 
Challenges of M&A

For more than four decades, the MedTech industry has predominantly relied on M&A as its primary growth strategy, which, over time led to the financialisaton of the industry. Larger conglomerates emerged, but their size does not always translate into enhanced patient outcomes or improved operational efficiency. This pattern emphasises a tendency where short-term financial objectives frequently overshadow longer-term strategies focused on quality systems, organisational structure, and talent within the acquired companies.
In many instances, early-stage enterprises have deficiencies in their operational and human resource systems. These weaknesses are frequently overlooked or insufficiently addressed during the integration phase. While the repercussions of such oversight might not be readily apparent, they tend to surface over time, potentially hindering growth.
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The Financialization Dilemma of MedTechs

 
The fallout from prioritising financial integration strategies can jeopardise the long-term viability of the merged entity and hamper its ability to innovate and adapt to shifting market dynamics. Successfully merging disparate corporate cultures, technological platforms, and operational processes requires meticulous planning and execution across all facets of the integration process. Neglecting to allocate adequate time and resources to address these non-financial aspects can lead to disruptions in workflow, employee discontent, and diminished performance.
 
Moving forward, corporations might consider adopting a more balanced approach to growth, one that not only factors in financial gains but also prioritises the assimilation of quality systems, organisational coherence, and human capital to ensure sustained success. Strategic complacency seems to be present in many large entities, and associated with an excessive dependence on conventional M&A for growth can dampen internal innovation.
 
Challenges of In-House R&D

Traditional MedTechs encounter challenges when considering disruptive in-house R&D endeavours. The inherent risks, coupled with resource constraints, often dissuade many traditional companies from pursuing innovative avenues of development. Also, complex regulatory environments present hurdles that require expertise, investment, and stringent compliance measures. The infrastructural needs for integrating new technologies exacerbate the situation, necessitating updates to current manufacturing facilities, supply chains, and distribution networks. These conditions emphasise the demanding nature of pursuing innovative R&D in-house. 

The demands of sales and marketing add additional complexity to internal development initiatives. New offerings require educating healthcare providers and consumers regarding their benefits, alongside developing specialised sales teams and tailored marketing strategies aligned with the product's unique demands. Incentivising sales teams to prioritise new offerings over established ones can be testing, which reinforces the hesitation of traditional MedTechs to pursue disruptive R&D projects.

 
A culture of risk aversion often prevails within traditional firms, leading to a reluctance to depart from established business models and technologies. This is reinforced by corporate structures that highlight stability and predictability over innovation and agility. Executives may hesitate to invest in ground-breaking R&D projects, opting instead for incremental improvements to existing devices. The allure of legacy products, despite their age and slow growth rates, provides a sense of security that dissuades corporations from exploring new technologies.
 
A Third Way

A Third Way for achieving growth and competitiveness, involves investing in innovative early-stage enterprises. Start-up culture thrives on creativity, fuelled by agility, entrepreneurial spirit, and a focus on disruptive solutions. Unlike traditional MedTechs, new ventures are free from the constraints of legacy systems, which enables them to take bold risks and explore new ideas. The collaborative culture of emerging businesses frequently attracts top talent from diverse disciplines, promoting interdisciplinary cooperation and fresh perspectives. This convergence of talent, flexibility, and risk-taking propels start-ups to the forefront of progress, extending the boundaries of what is achievable and contributing to transformative change in healthcare delivery and patient outcomes.
 
Engagement with entrepreneurial businesses warrants larger companies access to cutting-edge technologies while mitigating risk across a portfolio of ventures. Investment in early-stage entities opens avenues for collaboration, partnership, and potential acquisitions, enabling traditional firms to capitalise on emerging trends to maintain and enhance their competitiveness. Overall, embracing a broad-based investment strategy in start-ups represents a prudent approach for traditional MedTechs aiming to reconcile progress with risk.
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Healthcare disrupters

Supporting a variety of new ventures that are developing novel products through off-balance sheet investments presents a strategic advantage for traditional corporations. This approach allows them to access advancements without immediately bearing the financial burden of traditional acquisitions, thereby preserving their financial flexibility, and safeguarding their core business. 
By providing tax benefits and mitigating the impact on financial ratios, these commitments contribute to the overall financial wellbeing of the company. Additionally, they facilitate low-risk incremental acquisitions. As start-ups mature and demonstrate success, traditional enterprises can acquire them, leveraging their initial investment and minimising the risk associated with unproven technologies. This model fosters an ecosystem where new entrepreneurial entities thrive with support from established players.
 
Investing in emerging businesses for MedTechs extends beyond financial contributions and can include injections of expertise and knowledge. Established firms possess the capability to offer invaluable guidance and mentorship, drawing on their experience in navigating complex regulations, executing successful clinical trials, and effectively scaling manufacturing operations. By sharing their expertise and knowhow, mature companies amplify the impact of their financial stakes and strengthen their ability and reputation to drive innovation. 

 
The Potential of Venture Arms for MedTechs

The creation of venture arms by leading MedTech companies has facilitated creativity and driven commercial success. Johnson & Johnson (J&J) and Medtronic, for example, have embraced this trend with positive outcomes. J&J's venture initiative, JLabs, was initiated in 2015 in San Francisco to nurture ~50 start-ups across a spectrum of healthcare sectors, including medical devices and digital health. Since then, it has burgeoned into a dynamic ecosystem with key incubation hubs worldwide, from New York to China.
 
While J&J typically refrains from immediate investments, its strategic commitments to enterprises like Mauna Kea Technologies, Protekt Therapeutics, Cara Care, Cala Health, and Sight Diagnostics demonstrate the company's interest in nurturing entrepreneurial solutions aligned with its strategic objectives. Similarly, Medtronic's venture arm has effectively made strategic investments in a diverse array of early-stage businesses, with Axonics as a notable example. Axonics' recent (January 2023) FDA approval for its fourth-generation rechargeable sacral neuromodulation system serves as a testament to the success that can arise from such collaborative endeavours.
 
Traditional MedTech companies can take valuable lessons from industry giants such as J&J and Medtronic, especially in establishing their own venture funds to invest in a range of start-ups. This strategic manoeuvre not only provides these companies access to cutting-edge technologies and disruptive innovations that might outstrip their internal development capacities but also allows them to diversify their product portfolio and helps mitigate risks associated with reliance on a narrow range of offerings.
 
Entrepreneurial ventures often boast agility, enabling them to swiftly bring products to market, surmount bureaucratic hurdles that larger corporations may face, cultivate a culture centred on innovation within their organisations, and inspire employees to explore fresh ideas and collaborate with external partners. 
However, this can only be achieved if the MedTech market offers realistic opportunities.
 
The MedTech Start-up Market

We have argued that the MedTech start-up market holds potential for traditional companies seeking to revitalise their portfolios to maintain and increase their competitiveness. However, what are the realities of this market? Recent studies shed light on its trends and opportunities, and from these, we can judge whether such investments strategies are a viable option for mature MedTechs.

A 2017 study by the Deloitte Center for Health Solutions and AdvaMed Accel suggested that venture capital investments in early-stage MedTechs were slowing because alongside lacklustre returns, investors showed reluctance towards unproven technologies, and were deterred by regulatory and reimbursement obstacles. However, findings of a similar study repeated in 2021 paint a more promising picture. Since 2017 and the onset of the Covid-19 pandemic in 2020, venture financing in early stage MedTechs surged by ~67%, suggesting a renewed investor confidence. Notably, the bulk of investments were towards late-stage diagnostic and digital companies, highlighting a shift in investor priorities towards more mature ventures. Furthermore, alternative financing avenues such as public markets and family offices have emerged as viable options, opening new pathways for entrepreneurial endeavours. Notwithstanding, amidst this surge, seed, and Series A funding continued to decline, which poses difficulties for fledgling MedTech entities.

For traditional MedTech companies contending with aging legacy products in slow-moving markets, bridging the funding gap presents an opportunity to enhance their growth prospects and strengthen their competitive position. As we have asserted, beyond financial backing, start-ups often seek guidance on regulatory navigation, clinical studies, intellectual property, and reimbursement procedures. Leveraging their wealth of experience and established networks, large firms are ideally situated to provide such valuable insights and support to emerging ventures. 

 
Takeaways

By strategically committing to a diverse range of start-ups, traditional firms bolster their capacity to navigate the complexities of the technology ecosystem. This proactive stance not only positions enterprises to shape the future of healthcare but also augments their prospects for sustained growth and competitiveness in an industry experiencing rapid evolution.
 
Collaborating with emerging businesses at the forefront of technological development empowers large corporations to respond adeptly to market dynamics and drive progress. Such strategic engagement reinforces their relevance in the market, fosters a culture of cooperation and improvement across the healthcare continuum, strengthens traditional enterprises' competitive edge and ensures their long-term viability.
 
The entrepreneurial spirit inherent in start-ups can rejuvenate the development pipelines of traditional MedTechs, enhancing their decision-making and cultivating an environment of creativity conducive to growth. Establishing a fund to invest in start-ups helps to reduce risk and maximise returns, thus protecting corporations against potential disruptions. Adaptation is crucial for survival, and the approach outlined in this Commentary provides traditional companies reliant on legacy offerings with an opportunity to adapt and thrive, reaffirming their relevance in an era characterised by constant change.
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